Information for Researchers

If you are a researcher who would like to use BrainHQ in a study, please email us and we will direct you to Posit Science research team.

For your reference, below is a list (organized by subject population) of completed studies in which one or more BrainHQ exercises were used as an intervention.

 

ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)

  • Mishra J, Sagar R et al. Training sensory signal-to-noise resolution in children with ADHD in a global mental health setting. Translational Psychiatry. 2016 Apr;6:e781.
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  • Mishra J, Merzenich M, Sagar R. Accessible online neuroplasticity-targeted training for children with ADHD. Child and Adolescent Psychiatry and Mental Health. 2013 Nov 14;7:38.
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AUTISM SPECTRUM DISORDER

  • Tseng, Angela, Megan DuBois, Bruno Biagianti, Caroline Brumley, and Suma Jacob. 2023. “Auditory Domain Sensitivity and Neuroplasticity-Based Targeted Cognitive Training in Autism Spectrum Disorder.” Journal of Clinical Medicine 12 (4): 1635.
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BI-POLAR DISORDER

  • Lewandowski, Kathryn E., Sarah H. Sperry, Bruce M. Cohen, Lesley A. Norris, Garrett M. Fitzmaurice, Dost Ongur, and Matcheri S. Keshavan. 2017. “Treatment to Enhance Cognition in Bipolar Disorder (TREC-BD): Efficacy of a Randomized Controlled Trial of Cognitive Remediation versus Active Control.” The Journal of Clinical Psychiatry 78 (9): 1242–49.
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BrainHQ COGNITIVE ASSESSMENT VALIDATION

    • Runge, Shannon K., Elizabeth M. Hudak, Jade A. Sutfin, Victor R. Dobrovolskiy, and Jerri D. Edwards. 2025. “Validity and Reliability of the Online Useful Field of View Test among Community-Dwelling Older Adults.” Journal of Clinical and Experimental Neuropsychology 47 (1–2): 55–66.
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    • Zheng, Chanying, Yuting Cao, Yuyang Li, Zhoucheng Ye, Xize Jia, Mengting Li, Yang Yu, and Wenming Liu. 2024. “Long-Term Table Tennis Training Alters Dynamic Functional Connectivity and White Matter Microstructure in Large Scale Brain Regions.” Brain Research 1838:148889.
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    • Vance, David E., Pariya L. Fazeli, Andres Azuero, Jennifer S. Frank, Virginia G. Wadley, James L. Raper, Caitlin N. Pope, and Karlene K. Ball. 2024. “A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study.” AIDS and Behavior 28 (10): 3300–3314.
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    • Lee, Pai-Lin, Chih-Kun Huang, Yi-Yi Chen, Hui-Hsiang Chang, Chun-Hua Cheng, Yu-Chih Lin, and Chia-Li Lin. 2024. “Enhancing Cognitive Function in Older Adults through Processing Speed Training: Implications for Cognitive Health Awareness.” Healthcare 12 (5): 532.
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    • Attarha, Mouna, Henry Mahncke, and Michael Merzenich. 2024. “The Real-World Usability, Feasibility, and Performance Distributions of Deploying a Digital Toolbox of Computerized Assessments to Remotely Evaluate Brain Health: Development and Usability Study.” JMIR Formative Research 8 (1): e53623.
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    • Stefanidis, K. B., T. Mieran, C. Schiemer, J. Freeman, V. Truelove, and M. J. Summers. 2023. “Cognitive Correlates of Reduced Driving Performance in Healthy Older Adults: A Meta-Analytic Review.” Accident Analysis & Prevention 193:107337.
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    • Mahzarnia, Ali, Jacques A. Stout, Robert J. Anderson, Hae Sol Moon, Zay Yar Han, Kate Beck, Jeffrey N. Browndyke, et al. 2023. “Identifying Vulnerable Brain Networks Associated with Alzheimer’s Disease Risk.” Cerebral Cortex (New York, N.Y.: 1991) 33 (9): 5307–22.
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    • Biagianti, Bruno, Christine Conelea, Sawsan Dabit, Daniel Ross, Katie L. Beard, Elizabeth Harris, Erin Shen, Josh Jordan, and Gail A. Bernstein. 2023. “A Mobile Application Adjunct to Augment Cognitive–Behavioral Group Therapy for Adolescents with Social Anxiety: Feasibility and Acceptability Results from the Wiring Adolescents with Social Anxiety via Behavioral Interventions Pilot Trial.” Journal of Child and Adolescent Psychopharmacology.
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    • Maeir, Talia, Mor Nahum, Chen Makranz, Shani Tsabari, Tamar Peretz, and Yafit Gilboa. 2022. “Predictors of Quality of Life among Adults with Self-Reported Cancer Related Cognitive Impairment.” Disability and Rehabilitation 0 (0): 1–7.
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    • Mackenzie, Andrew K., Mike L. Vernon, Paul R. Cox, David Crundall, Rosie C. Daly, Duncan Guest, Alexander Muhl-Richardson, and Christina J. Howard. 2022. “The Multiple Object Avoidance (MOA) Task Measures Attention for Action: Evidence from Driving and Sport.” Behavior Research Methods 54 (3): 1508–29.
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    • Kraft, Jessica N., Alejandro Albizu, Andrew O’Shea, Hanna K. Hausman, Nicole D. Evangelista, Emanuel Boutzoukas, Cheshire Hardcastle, et al. 2022. “Functional Neural Correlates of a Useful Field of View (UFOV)-Based FMRI Task in Older Adults.” Cerebral Cortex (New York, N.Y.: 1991), bhab332.
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    • Kraft, Jessica N., Hanna K. Hausman, Cheshire Hardcastle, Alejandro Albizu, Andrew O’Shea, Nicole D. Evangelista, Emanuel M. Boutzoukas, et al. 2022. “Task-Based Functional Connectivity of the Useful Field of View (UFOV) FMRI Task.” GeroScience.
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    • Eastman, Jennifer, Allison Kaup, A Bahorik, X Butcher, M Attarha, G Marcus, M Pletcher, J Olgin, Deborah Barnes, and Kristine Yaffe. 2022. “Remote Assessment of Cardiovascular Risk Factors and Cognition in Middle-Aged and Older Adults: Proof-of-Concept Study.” JMIR Formative Research 6 (2).
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    • Soldevila-Domenech, Natalia, Laura Forcano, Anna Boronat, Thais Lorenzo, Iris Piera, Albert Puig-Pijoan, Julian Mateus, et al. 2021. “Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease.” Journal of Alzheimer’s Disease 79 (3): 1015–21.
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    • Shimony, Orly, Noam Einav, Omer Bonne, Joshua T. Jordan, Thomas M. Van Vleet, and Mor Nahum. 2021. “The Association between Implicit and Explicit Affective Inhibitory Control, Rumination and Depressive Symptoms.” Scientific Reports 11 (1): 11490.
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    • Richer, Stuart, Steven Novil, Taylor Gullett, Avni Dervishi, Sherwin Nassiri, Co Duong, Robert Davis, and Pinakin Gunvant Davey. 2021. “Night Vision and Carotenoids (NVC): A Randomized Placebo Controlled Clinical Trial on Effects of Carotenoid Supplementation on Night Vision in Older Adults.” Nutrients 13 (9): 3191.
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    • Hemptinne, Coralie de, Witney Chen, Caroline A. Racine, Andreea L. Seritan, Andrew M. Miller, Maria S. Yaroshinsky, Sarah S. Wang, et al. 2021. “Prefrontal Physiomarkers of Anxiety and Depression in Parkinson’s Disease.” Frontiers in Neuroscience 15.
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    • Capizzi, Riley, Melissa Fisher, Bruno Biagianti, Neelufaer Ghiasi, Ariel Currie, Karrie Fitzpatrick, Nicholas Albertini, and Sophia Vinogradov. 2021. “Testing a Novel Web-Based Neurocognitive Battery in the General Community: Validation and Usability Study.” Journal of Medical Internet Research 23 (5): e25082.
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    • Yaffe, Kristine, Allison R. Kaup, Amber L. Bahorik, Xochitl Butcher, Mouna Attarha, Gregory M. Marcus, Mark J. Pletcher, and Jeffrey E. Olgin. 2020. “Web-Based Assessment of Cardiovascular Risk Factors and Cognition in Older Adults: Findings from the Brain EHealth Feasibility Study.” Alzheimer’s & Dementia 16 (S10): e041212.
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    • Ramsay, Ian S., Michael-Paul Schallmo, Bruno Biagianti, Melissa Fisher, Sophia Vinogradov, and Scott R. Sponheim. 2020. “Deficits in Auditory and Visual Sensory Discrimination Reflect a Genetic Liability for Psychosis and Predict Disruptions in Global Cognitive Functioning.” Frontiers in Psychiatry 11.
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    • Harenberg, Sebastian, Jennifer St Onge, Jill Robinson, Omorowa Eguakun, Anthony Feinstein, Kim Dorsch, Rumit Singh Kakar, et al. 2020. “The Effectiveness of 3-Dimensional Multiple Object Tracking in Patients with Multiple Sclerosis: A Pilot Trial3D Multiple Object Tracking in MS.” International Journal of MS Care.
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    • Chernoff, Andie, Ashley A. Balsom, and Jennifer L. Gordon. 2020. “Psychological Coping Strategies Associated with Improved Mental Health in the Context of Infertility.” Archives of Women’s Mental Health.
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    • Boroda, Elias, Alyssa M. Krueger, Priya Bansal, Mariah J. Schumacher, Abhrajeet V. Roy, Christopher J. Boys, Kelvin O. Lim, and Jeffrey R. Wozniak. 2020. “A Randomized Controlled Trial of Transcranial Direct-Current Stimulation and Cognitive Training in Children with Fetal Alcohol Spectrum Disorder.” Brain Stimulation 13 (4): 1059–68.
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    • Biagianti, Bruno, Melissa Fisher, Rachel Loewy, Benjamin Brandrett, Catalina Ordorica, Kristin LaCross, Brandon Schermitzler, Michelle McDonald, Ian Ramsay, and Sophia Vinogradov. 2020. “Specificity and Durability of Changes in Auditory Processing Efficiency after Targeted Cognitive Training in Individuals with Recent-Onset Psychosis.” Frontiers in Psychiatry 11.
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    • Van Vleet, Thomas, Alit Stark, Michael M. Merzenich, Josh Jordan, Deanna L. Wallace, Morgan B. Lee, Heather E. Dawes, Edward F. Chang, and Mor Nahum. 2019. “Biases in Processing of Mood-Congruent Facial Expressions in Depression.” Psychiatry Research 275:143–48.
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    • Biagianti, Bruno, Melissa Fisher, Benjamin Brandrett, Danielle Schlosser, Rachel Loewy, Mor Nahum, and Sophia Vinogradov. 2019. “Development and Testing of a Web-Based Battery to Remotely Assess Cognitive Health in Individuals with Schizophrenia.” Schizophrenia Research.
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    • Sani, Omid G., Yuxiao Yang, Morgan B. Lee, Heather E. Dawes, Edward F. Chang, and Maryam M. Shanechi. 2018. “Mood Variations Decoded from Multi-Site Intracranial Human Brain Activity.” Nature Biotechnology 36 (10): 954–61.
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    • Rao, Vikram R., Kristin K. Sellers, Deanna L. Wallace, Morgan B. Lee, Maryam Bijanzadeh, Omid G. Sani, Yuxiao Yang, Maryam M. Shanechi, Heather E. Dawes, and Edward F. Chang. 2018. “Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression.” Current Biology 28 (24): 3893-3902.e4.
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    • Kirkby, Lowry A., Francisco J. Luongo, Morgan B. Lee, Mor Nahum, Thomas M. Van Vleet, Vikram R. Rao, Heather E. Dawes, Edward F. Chang, and Vikaas S. Sohal. 2018. “An Amygdala-Hippocampus Subnetwork That Encodes Variation in Human Mood.” Cell 175 (6): 1688-1700.e14.
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    • Nahum, Mor, Thomas M. Van Vleet, Vikaas S. Sohal, Julie J. Mirzabekov, Vikram R. Rao, Deanna L. Wallace, Morgan B. Lee, et al. 2017. “Immediate Mood Scaler: Tracking Symptoms of Depression and Anxiety Using a Novel Mobile Mood Scale.” JMIR MHealth and UHealth 5 (4): e6544.
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CANCER-RELATED COGNITIVE IMPAIRMENT

      • Areklett, E. W., B. I. Hagen, J. Stubberud, E. Fagereng, S. Andersson, and K. Lindemann. 2024. “Digital Goal Management Training for Cognitive Impairment in Cervical Cancer Survivors—a Randomized Comparison Study.” Journal of Cancer Survivorship.
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      • Von Ah, Diane, Adele Crouch, and Susan Storey. 2023. “Acceptability of Computerized Cognitive Training and Global Cognitive Stimulating-Based Games Delivered Remotely: Results from a Randomized Controlled Trial to Address Cancer and Cancer-Related Cognitive Impairment in Breast Cancer Survivors.” Cancer Medicine 12 (11): 12717–27.
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      • Maeir, Talia, Chen Makranz, Tamar Peretz, Ester Odem, Shani Tsabari, Mor Nahum, and Yafit Gilboa. 2023. “Cognitive Retraining and Functional Treatment (CRAFT) for Adults with Cancer Related Cognitive Impairment: A Preliminary Efficacy Study.” Supportive Care in Cancer 31 (3): 152.
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      • Von Ah, Diane, Brenna C. McDonald, Adele D. Crouch, Susan Ofner, Susan Perkins, Susan Storey, Robert Considine, and Fred Unverzagt. 2022. “Randomized Double-Masked Controlled Trial of Cognitive Training in Breast Cancer Survivors: A Preliminary Study.” Supportive Care in Cancer, June.
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      • Meneses, Karen, Rachel Benz, Jennifer R. Bail, Jacqueline B. Vo, Kristen Triebel, Pariya Fazeli, Jennifer Frank, and David E. Vance. 2018. “Speed of Processing Training in Middle-Aged and Older Breast Cancer Survivors (SOAR): Results of a Randomized Controlled Pilot.” Breast Cancer Research and Treatment 168 (1): 259–67.
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      • Bray, Victoria J., Haryana M. Dhillon, Melanie L. Bell, Michael Kabourakis, Mallorie H. Fiero, Desmond Yip, Frances Boyle, Melanie A. Price, and Janette L. Vardy. 2017. “Evaluation of a Web-Based Cognitive Rehabilitation Program in Cancer Survivors Reporting Cognitive Symptoms after Chemotherapy.” Journal of Clinical Oncology 35 (2): 217–25.
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      • Von Ah, Diane, Janet S. Carpenter, Andrew Saykin, Patrick Monahan, Jingwei Wu, Menggang Yu, George Rebok, et al. 2012. “Advanced Cognitive Training for Breast Cancer Survivors: A Randomized Controlled Trial.” Breast Cancer Research and Treatment 135 (3): 799–809.
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CONDUCT DISORDER

      • Rowlands, Abby, Melissa Fisher, Jyoti Mishra, Mor Nahum, Benjamin Brandrett, Michael Reinke, Michael Caldwell, Kent A. Kiehl, and Sophia Vinogradov. 2020. “Cognitive Training for Very High Risk Incarcerated Adolescent Males.” Frontiers in Psychiatry 11.
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DEMENTIA

      • Roach, Jared C., Molly K. Rapozo, Junko Hara, Gwênlyn Glusman, Jennifer Lovejoy, William R. Shankle, and Leroy Hood. 2023. “A Remotely Coached Multimodal Lifestyle Intervention for Alzheimer’s Disease Ameliorates Functional and Cognitive Outcomes.” Journal of Alzheimer’s Disease, 591–607.
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      • Toups, Kat, Ann Hathaway, Deborah Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, et al. 2022. “Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.” Journal of Alzheimer’s Disease 88 (January): 1411–21.
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      • Rouse, Hillary J., Brent J. Small, and Mark E. Faust. 2019. “Assessment of Cognitive Training & Social Interaction in People with Mild to Moderate Dementia: A Pilot Study.” Clinical Gerontologist 42 (4): 421–34.
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      • Edwards, Jerri D., Huiping Xu, Daniel O. Clark, Lin T. Guey, Lesley A. Ross, and Frederick W. Unverzagt. 2017. “Speed of Processing Training Results in Lower Risk of Dementia.” Alzheimer’s & Dementia: Translational Research & Clinical Interventions 3 (4): 603–611.
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DEPRESSION

      • Szymkowicz, Sarah M., Warren D. Taylor, and Adam J. Woods. 2022. “Augmenting Cognitive Training with Bifrontal TDCS Decreases Subclinical Depressive Symptoms in Older Adults: Preliminary Findings.” Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation 15 (5): 1037–39.
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      • Hagen, Bjørn Ingulfsvann, Nils Inge Landrø, Bjørn Lau, Ernst H. W. Koster, and Jan Stubberud. 2020. “Predictors of Long-Term Improvement Following Cognitive Remediation in a Sample with Elevated Depressive Symptoms.” Frontiers in Psychology 11.
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      • Hagen, Bjørn Ingulfsvann, Bjørn Lau, Jutta Joormann, Milada Cvancarova Småstuen, Nils Inge Landrø, and Jan Stubberud. 2020. “Goal Management Training as a Cognitive Remediation Intervention in Depression: A Randomized Controlled Trial.” Journal of Affective Disorders 275 (October): 268–77.
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      • Morimoto, Sarah Shizuko, Roger Alan Altizer, Faith M. Gunning, Willie Hu, Jiacheng Liu, Sarah E. Cote, Juliana Nitis, and George S. Alexopoulos. 2020. “Targeting Cognitive Control Deficits with Neuroplasticity-Based Computerized Cognitive Remediation in Patients with Geriatric Major Depression: A Randomized, Double-Blind, Controlled Trial.” The American Journal of Geriatric Psychiatry 28 (9): 971–80.
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      • Mao, Ronghua, Changxiang Chen, Dan Li, Shuxing Li, and Min Zhang. 2015. “Intervention Effect of BrainHQ Visual Training on Depressive Symptom in Patients with Post Stroke Depression.” Chinese Journal of Behavioral Medical Science 24 (12): 1097–99.
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      • Wolinsky, Fredric D., Mark W. Vander Weg, M. Bryant Howren, Michael P. Jones, and Megan M. Dotson. 2015. “The Effect of Cognitive Speed of Processing Training on the Development of Additional IADL Difficulties and the Reduction of Depressive Symptoms Results from the IHAMS Randomized Controlled Trial.” Journal of Aging and Health 27 (2): 334–54.
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      • Morimoto, Sarah Shizuko, Bruce E. Wexler, Jiacheng Liu, Willie Hu, Joanna Seirup, and George S. Alexopoulos. 2014. “Neuroplasticity-Based Computerized Cognitive Remediation for Treatment-Resistant Geriatric Depression.” Nature Communications 5 (4579): 1–7.
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      • Wolinsky, F D, H W Mahncke, M W Vander Weg, R Martin, F W Unverzagt, K K Ball, R N Jones, and S L Tennstedt. 2009. “The ACTIVE Cognitive Training Interventions and the Onset of and Recovery from Suspected Clinical Depression.” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 64 (5): 577–85.
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      • Wolinsky, F. D., M. W. Vander Weg, R Martin, F. W. Unverzagt, K. K. Ball, R. N. Jones, and S. L. Tennstedt. 2009. “The Effect of Speed-of-Processing Training on Depressive Symptoms in ACTIVE.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 64 (4): 468–72.
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DIABETES

      • Oki, Yutaro, Tohmi Osaki, Ryoko Kumagai, Shunsuke Murata, Haruhi Encho, Rei Ono, Hisafumi Yasuda, and Hisatomo Kowa. 2024. “An 18-Month Multimodal Intervention Trial for Preventing Dementia: J-MINT PRIME Tamba.” Alzheimer’s & Dementia 20 (10): 6972–83.
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      • McEvoy, Claire T., Joanne Regan-Moriarty, Catherine Dolan, Caroline Bradshaw, Valerie Mortland, Maire McCallion, Geraldine McCarthy, et al. 2023. “A Qualitative Study to Inform Adaptations to a Brain Health Intervention for Older Adults with Type 2 Diabetes Living in Rural Regions of Ireland.” Diabetic Medicine 40 (4): e15034.
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      • Natovich, Rachel, Noa Gayus, Michal Azmon, Hila Michal, Omri Gury Twito, Tomer Yair, Svetlana Raudoi, Ori Kapra, and Tali Cukierman-Yaffe. 2020. “A Comprehensive Intervention for Promoting Successful Aging amongst Older People with Diabetes with Below-Normal Cognitive Function—a Feasibility Study.” Frontiers in Endocrinology 11.
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      • Cuevas, Heather E., Alexa K. Stuifbergen, Sharon A. Brown, and Catherine Ward. 2019. “A Nurse-Led Cognitive Training Intervention for Individuals With Type 2 Diabetes.” Research in Gerontological Nursing 12 (4): 203–12.
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DOWN SYNDROME

      • Merzbach, Viviane, Matthew Jewiss, Adrian Scruton, and Dan Gordon. 2024. “The Effects of Prescribed Physical and Cognitive Exercise on Life Satisfaction, Self-Efficacy and Mood States in Adults with Down Syndrome: The MinDSets Study.” International Journal of Environmental Research and Public Health 21 (5): 610.
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      • Merzbach, Viviane, Michael Ferrandino, Marie Gernigon, Jorge Marques Pinto, Adrian Scruton, and Dan Gordon. 2023. “Impact of Prescribed Exercise on the Physical and Cognitive Health of Adults with Down Syndrome: The MinDSets Study.” International Journal of Environmental Research and Public Health 20 (23): 7121.
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      • Anagnostopoulou, Alexandra, Charis Styliadis, Panagiotis Kartsidis, Evangelia Romanopoulou, Vasiliki Zilidou, Chrysi Karali, Maria Karagianni, Manousos Klados, Evangelos Paraskevopoulos, and Panagiotis D. Bamidis. 2021. “Computerized Physical and Cognitive Training Improves the Functional Architecture of the Brain in Adults with Down Syndrome: A Network Science EEG Study.” Network Neuroscience 5 (1): 274–94.
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HEALTHY ADULTS / HEALTHY AGING

    • Woodruff, Erica, Bruno Costa Poltronieri, Luisa Pedrosa de Albuquerque Sousa, Yasmin Guedes de Oliveira, Marcos Alexandre Reis, Linda Scoriels, and Rogério Panizzutti. 2024. “Effects of Bottom-up versus Top-down Digital Cognitive Training in Older Adults: A Randomized Controlled Trial.” Archives of Gerontology and Geriatrics 127:105552.
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    • Lee, Pai-Lin, Chih-Kun Huang, Yi-Yi Chen, Hui-Hsiang Chang, Chun-Hua Cheng, Yu-Chih Lin, and Chia-Li Lin. 2024. “Enhancing Cognitive Function in Older Adults through Processing Speed Training: Implications for Cognitive Health Awareness.” Healthcare 12 (5): 532.
      View article
    • Lee, Hyun Kyu, Chandramallika Basak, Sarah-Jane Grant, Nicholas R Ray, Paulina A Skolasinska, Chris Oehler, Shuo Qin, et al. 2024. “The Effects of Computerized Cognitive Training in Older Adults’ Cognitive Performance and Biomarkers of Structural Brain Aging.” The Journals of Gerontology: Series B, gbae075.
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    • Huang, Alison R., George W. Rebok, Bonnielin K. Swenor, and Jennifer A. Deal. 2024. “Vision and Hearing Difficulty and Effects of Cognitive Training in Older Adults.” Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 16 (2): e12537.
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    • Hausman, Hanna K., Gene E. Alexander, Ronald Cohen, Michael Marsiske, Steven T. DeKosky, Georg A. Hishaw, Andrew O’Shea, et al. 2024. “TDCS Reduces Depression and State Anxiety Symptoms in Older Adults from the Augmenting Cognitive Training in Older Adults Study (ACT).” Brain Stimulation.
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    • Hardcastle, Cheshire, Jessica N. Kraft, Hanna K. Hausman, Andrew O’Shea, Alejandro Albizu, Nicole D. Evangelista, Emanuel M. Boutzoukas, et al. 2024. “Learning Ratio Performance on a Brief Visual Learning and Memory Test Moderates Cognitive Training Gains in Double Decision Task in Healthy Older Adults.” GeroScience.
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    • Funghi, Giulia, Claudia Meli, Arianna Cavagna, Lisa Bisoffi, Francesca Zappini, Costanza Papagno, and Alessandra Dodich. 2024. “The Social and Cognitive Online Training (SCOT) Project: A Digital Randomized Controlled Trial to Promote Socio-Cognitive Well-Being in Older Adults.” Archives of Gerontology and Geriatrics 122:105405.
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    • Aksu, Serkan, Aprinda Indahlastari, Andrew O’Shea, Michael Marsiske, Ronald Cohen, Gene E. Alexander, Steven T. DeKosky, et al. 2024. “Facilitation of Working Memory Capacity by Transcranial Direct Current Stimulation: A Secondary Analysis from the Augmenting Cognitive Training in Older Adults (ACT) Study.” GeroScience 46 (5): 4075–4110.
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    • Wallace, Gail, Tyler Bell, Sheila Black, Michael Crowe, Roland J. Thorpe, Caitlin Pope, and George W. Rebok. 2023. “Associations of Subjective Memory with Life Space and Neighborhood Built Environment in Older Adults in the ACTIVE Study.” Journal of Aging and Health 36 (3–4): 161–69.
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    • Sprague, Briana N., Lesley A. Ross, and Karlene K. Ball. 2023. “Does Cognitive Training Reduce Falls across Ten Years?: Data from the ACTIVE Trial.” International Journal of Environmental Research and Public Health 20 (6): 4941.
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    • Rotblatt, Lindsay J., Adrienne T. Aiken-Morgan, Michael Marsiske, Ann L. Horgas, and Kelsey R. Thomas. 2023. “Do Associations Between Vascular Risk and Mild Cognitive Impairment Vary by Race?” Journal of Aging and Health 35 (9_suppl): 74S-83S.
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    • Rebok, George W., Andrew Gellert, Norma B. Coe, Olivio J. Clay, Gail Wallace, Jeanine M. Parisi, Adrienne T. Aiken-Morgan, et al. 2023. “Effects of Cognitive Training on Alzheimer’s Disease and Related Dementias: The Moderating Role of Social Determinants of Health.” Journal of Aging and Health 35 (9_suppl): 40S-50S.
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    • Rebok, George W., Olivio J. Clay, Roland J. Thorpe, and Sherry L. Willis. 2023. “The ACTIVE Study: Association of Race and Social Determinants of Health (SDoH) with Long-Term Outcomes and Cognitive Training Effects.” Journal of Aging and Health 35 (9_suppl): 3S-10S.
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    • Pope, Caitlin N., Katie M. Wheeler, Tyler R. Bell, Brooke E. Carroll, Lesley A. Ross, Michael Crowe, Shelia R. Black, Olivio J. Clay, and Karlene K. Ball. 2023. “Social and Neighborhood Context Moderates the Associations Between Processing Speed and Driving Mobility: A 10-Year Analysis of the ACTIVE Study.” Journal of Aging and Health 35 (9_suppl): 26S-39S.
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    • Owens, Joshua, Richard Jones, and Michael Marsiske. 2023. “The Effects of Occupational Complexity on Late Life Cognition in ACTIVE: Examining the Mediating and Moderating Effects of Race.” Journal of Aging and Health 35 (9_suppl): 95S-106S.
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    • Lewis, Erin D., Margaret Apostol, Jamie Langston, Alex Parker, and Malkanthi Evans. 2023. “A Multi-Center, Open-Label Exploratory Study to Assess Cognitive Function Response to Lifestyle Changes Plus Supplementation in Healthy Adults with Risk Factors Associated with Cognitive Decline.” Applied Sciences 13 (5): 2818.
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    • Hausman, Hanna K., Gene E. Alexander, Ronald Cohen, Michael Marsiske, Steven T. DeKosky, Georg A. Hishaw, Andrew O’Shea, et al. 2023. “Primary Outcome from the Augmenting Cognitive Training in Older Adults Study (ACT): A TDCS and Cognitive Training Randomized Clinical Trial.” Brain Stimulation 16 (3): 904–17.
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    • Feger, Danielle M., Sherry L. Willis, Jennifer Deal, Lorraine T. Dean, and Alden L. Gross. 2023. “Disparities in First Instrumental Activity of Daily Living Difficulty between Black and White Older Adults: Findings from the Advanced Cognitive Training in Independent and Vital Elderly Study.” Journal of Aging and Health 35 (9_suppl): 51S-58S.
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    • Dean, Lorraine T., Shang-En Chung, Alden L. Gross, Olivio J. Clay, Sherry L. Willis, Michael Crowe, Ian M. McDonough, et al. 2023. “Does Consumer Credit Precede or Follow Changes in Cognitive Impairment Among Older Adults? An Investigation in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) Trial.” Journal of Aging and Health 35 (9_suppl): 84S-94S.
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    • Clay, Olivio J., Karlene K. Ball, Katie M. Wheeler, Michael Crowe, Michael Marsiske, Lorraine T. Dean, Roland J. Thorpe, et al. 2023. “Evaluating Social Determinants of Health Domains and Their Predictive Validity within Black/African American and White Older Adults from the ACTIVE Trial.” Journal of Aging and Health 35 (9_suppl): 11S-18S.
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    • Bruno, Jennifer L., Jacob S. Shaw, and S. M. Hadi Hosseini. 2023. “Toward Personalized Cognitive Training in Older Adults: A Pilot Investigation of the Effects of Baseline Performance and Age on Cognitive Training Outcomes.” Journal of Alzheimer’s Disease: JAD.
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    • Ball, Karlene K., Olivio J. Clay, Jerri D. Edwards, Bernadette A. Fausto, Katie M. Wheeler, Cynthia Felix, and Lesley A. Ross. 2023. “Indicators of Crash Risk in Older Adults: A Longitudinal Analysis From the ACTIVE Study.” Journal of Aging and Health 35 (9_suppl): 19S-25S.
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    • An, Yong Woo, Kyung-Min Kim, Andrea DiTrani Lobacz, Jochen Baumeister, Jill S. Higginson, Jeffrey Rosen, and Charles Buz Swanik. 2023. “Cognitive Training Improves Joint Stiffness Regulation and Function in ACLR Patients Compared to Healthy Controls.” Healthcare 11 (13): 1875.
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    • Aiken-Morgan, Adrienne T., Ian M. McDonough, Jeanine M. Parisi, Olivio J. Clay, Kelsey R. Thomas, Lindsay J. Rotblatt, Roland J. Thorpe, and Michael Marsiske. 2023. “Associations Between Body Mass Index and Cognitive Change in the ACTIVE Study: Variations by Race and Social Determinants of Health.” Journal of Aging and Health 35 (9_suppl): 59S-73S.
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    • Thorpe, Roland J., Alison Huang, Emily Smail, Olivio J. Clay, Lorraine Dean, Adrienne Aiken Morgan, Andrew Gellert, and George W. Rebok. 2022. “The Relationship between Cognition and Mortality among Older Black and White Men in Advanced Cognitive Training for Independent and Vital Elderly.” Journal of Aging and Health 35 (9_suppl): 119S-125S.
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    • Kraft, Jessica N., Hanna K. Hausman, Cheshire Hardcastle, Alejandro Albizu, Andrew O’Shea, Nicole D. Evangelista, Emanuel M. Boutzoukas, et al. 2022. “Task-Based Functional Connectivity of the Useful Field of View (UFOV) FMRI Task.” GeroScience.
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    • Hardcastle, Cheshire, Hanna K. Hausman, Jessica N. Kraft, Alejandro Albizu, Andrew O’Shea, Emanuel M. Boutzoukas, Nicole D. Evangelista, et al. 2022. “Proximal Improvement and Higher-Order Resting State Network Change after Multidomain Cognitive Training Intervention in Healthy Older Adults.” GeroScience.
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    • Clark, Alexandra L., Alexandra J. Weigand, Olivio J. Clay, Joshua Owens, Jacob Fiala, Michael Crowe, Michael Marsiske, and Kelsey R. Thomas. 2022. “Associations between Social Determinants of Health and 10-Year Change in Everyday Functioning within Black/African American and White Older Adults Enrolled in ACTIVE.” Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring 14 (1): e12385.
      View article
    • Bugos, Jennifer A, and Yan Wang. 2022. “Piano Training Enhances Executive Functions and Psychosocial Outcomes in Aging: Results of a Randomized Controlled Trial.” The Journals of Gerontology: Series B 77 (9): 1625–36.
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    • Boutzoukas, Emanuel M., Andrew O’Shea, Jessica N. Kraft, Cheshire Hardcastle, Nicole D. Evangelista, Hanna K. Hausman, Alejandro Albizu, et al. 2022. “Higher White Matter Hyperintensity Load Adversely Affects Pre-Post Proximal Cognitive Training Performance in Healthy Older Adults.” GeroScience 44:1441–55.
      View article
    • Routledge, Kylie M., Leanne M. Williams, Anthony W. F. Harris, Peter R. Schofield, and Justine M. Gatt. 2021. “The Impact of Online Brain Training Exercises on Experiences of Depression, Anxiety and Emotional Wellbeing in a Twin Sample.” Journal of Psychiatric Research 134:138–49.
      View article
    • Meltzer, Jed A., Mira Kates Rose, Anna Y. Le, Kiah A. Spencer, Leora Goldstein, Alina Gubanova, Abbie C. Lai, Maryam Yossofzai, Sabrina E.M. Armstrong, and Ellen Bialystok. 2021. “Improvement in Executive Function for Older Adults through Smartphone Apps: A Randomized Clinical Trial Comparing Language Learning and Brain Training.” Aging, Neuropsychology, and Cognition 30 (2): 150–71.
      View article
    • Hudak, Elizabeth M., Karen L. Bell, Cidnee Hall, Lori D. Grismore, Jake LaVere, and Jerri D. Edwards. 2021. “Dynamic Useful Field of View Training to Enhance Older Adults’ Cognitive and Motor Function: A Pilot Study.” Journal of Cognitive Enhancement.
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    • Ogawa, Elisa F., Haikun Huang, Lap-Fai Yu, Philimon N. Gona, Richard K. Fleming, Suzanne G. Leveille, and Tongjian You. 2020. “Effects of Exergaming on Cognition and Gait in Older Adults at Risk for Falling.” Medicine and Science in Sports and Exercise 52 (3): 754–61.
      View article
    • Lee, Hyun Kyu, James D. Kent, Christopher Wendel, Fredric D. Wolinsky, Eric D. Foster, Michael M. Merzenich, and Michelle W. Voss. 2020. “Home-Based, Adaptive Cognitive Training for Cognitively Normal Older Adults: Initial Efficacy Trial.” The Journals of Gerontology: Series B 75 (6): 1144–54.
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    • Edwards, Jerri D., Christine B. Phillips, Melissa L. O’Connor, Jennifer L. O’Brien, Elizabeth M. Hudak, and Jody S. Nicholson. 2020. “Applying the Health Belief Model to Quantify and Investigate Expectations for Computerized Cognitive Training.” Journal of Cognitive Enhancement.
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    • Czaja, Sara J., Peter Kallestrup, and Philip D. Harvey. 2020. “Evaluation of a Novel Technology-Based Program Designed to Assess and Train Everyday Skills in Older Adults.” Innovation in Aging 4 (6).
      View article
    • Walters, Jim, Stanley E. Sheft, Mark A. Stellmack, and Anna Abele. 2019. “Improving Attentiveness: Effect of Cognitive Training on Sustained Attention Measures.” Safety Research 64 (4): 31–35.
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    • Ross, Lesley A., Christina E. Webb, Christine Whitaker, Jarrod M. Hicks, Erica L. Schmidt, Shaadee Samimy, Nancy A. Dennis, and Kristina M. Visscher. 2019. “The Effects of Useful Field of View Training on Brain Activity and Connectivity.” The Journals of Gerontology: Series B 74 (7): 1152–62.
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    • Miller, Steven L., Suhas Chelian, Will McBurnett, Winnie Tsou, and Amy A. Kruse. 2019. “An Investigation of Computer-Based Brain Training on the Cognitive and EEG Performance of Employees.” 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 518–21.
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    • Hamilton, Joseph A., Gary Lambert, Joel Suss, and Adam T. Biggs. 2019. “Can Cognitive Training Improve Shoot/Don’t-Shoot Performance? Evidence from Live Fire Exercises.” The American Journal of Psychology 132 (2): 179–94.
      View article
    • Faust, Mark E., Kristi S. Multhaup, Michelle S. Ong, George J. Demakis, and Kelly G. Balz. 2019. “Exploring the Specificity, Synergy, and Durability of Auditory and Visual Computer Game Transfer Effects in Healthy Older Adults.” The Journals of Gerontology: Series B.
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    • Belchior, Patrícia, Anna Yam, Kelsey R. Thomas, Daphne Bavelier, Karlene K. Ball, William C. Mann, and Michael Marsiske. 2019. “Computer and Videogame Interventions for Older Adults’ Cognitive and Everyday Functioning.” Games for Health Journal 8 (2).
      View article
    • Gross, Alden L., Brennan R. Payne, Ramon Casanova, Pega Davoudzadeh, Joseph M. Dzierzewski, Sarah Farias, Tania Giovannetti, et al. 2018. “The ACTIVE Conceptual Framework as a Structural Equation Model.” Experimental Aging Research 44 (1): 1–17.
      View article
    • Eramudugolla, Ranmalee, Kim M. Kiely, Sidhant Chopra, and Kaarin J. Anstey. 2017. “Effect of Speed of Processing Training on Older Driver Screening Measures.” Frontiers in Aging Neuroscience 9:338.
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    • Edwards, Jerri D., Huiping Xu, Daniel O. Clark, Lin T. Guey, Lesley A. Ross, and Frederick W. Unverzagt. 2017. “Speed of Processing Training Results in Lower Risk of Dementia.” Alzheimer’s & Dementia: Translational Research & Clinical Interventions 3 (4): 603–11.
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    • Van Vleet, Thomas M., Joseph M. DeGutis, Michael M. Merzenich, Gregory V. Simpson, Ativ Zomet, and Sawsan Dabit. 2016. “Targeting Alertness to Improve Cognition in Older Adults: A Preliminary Report of Benefits in Executive Function and Skill Acquisition.” Cortex 82:100–118.
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    • Wolinsky, Fredric D., Mark W. Vander Weg, M. Bryant Howren, Michael P. Jones, and Megan M. Dotson. 2015. “Effects of Cognitive Speed of Processing Training on a Composite Neuropsychological Outcome: Results at One-Year from the IHAMS Randomized Controlled Trial.” International Psychogeriatrics 28 (2): 317–30.
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    • Wolinsky, Fredric D., Mark W. Vander Weg, M. Bryant Howren, Michael P. Jones, and Megan M. Dotson. 2015. “The Effect of Cognitive Speed of Processing Training on the Development of Additional IADL Difficulties and the Reduction of Depressive Symptoms Results from the IHAMS Randomized Controlled Trial.” Journal of Aging and Health 27 (2): 334–54.
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    • Smith-Ray, Renae L., Susan L. Hughes, Thomas R. Prohaska, Deborah M. Little, Donald A. Jurivich, and Donald Hedeker. 2015. “Impact of Cognitive Training on Balance and Gait in Older Adults.” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 70 (3): 357–66.
      View article
    • Ross, Lesley A., Jerri D. Edwards, Melissa L. O’Connor, Karlene K. Ball, Virginia G. Wadley, and David E. Vance. 2015. “The Transfer of Cognitive Speed of Processing Training to Older Adults’ Driving Mobility across 5 Years.” The Journals of Gerontology Series B: Psychological Sciences and Social Sciences 71 (1): 87–97.
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    • Mishra, Jyoti, Camarin Rolle, and Adam Gazzaley. 2015. “Neural Plasticity Underlying Visual Perceptual Learning in Aging.” Brain Research 1612:140–51.
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    • Clark, Daniel O., Huiping Xu, Frederick W. Unverzagt, and Hugh Hendrie. 2015. “Does Targeted Cognitive Training Reduce Educational Disparities in Cognitive Function among Cognitively Normal Older Adults?” International Journal of Geriatric Psychiatry 31 (7): 1099–1166.
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    • Bamidis, Panagiotis D., Patrick Fissler, Sokratis G. Papageorgiou, Vasiliki Zilidou, Evdokimos I. Konstantinidis, Antonis S. Billis, Evangelia Romanopoulou, et al. 2015. “Gains in Cognition through Combined Cognitive and Physical Training: The Role of Training Dosage and Severity of Neurocognitive Disorder.” Frontiers in Aging Neuroscience 7 (152): 1–15.
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    • Zelinski, Elizabeth M., Kelly D. Peters, Shoshana Hindin, Kevin T. Petway, and Robert F. Kennison. 2014. “Evaluating the Relationship between Change in Performance on Training Tasks and on Untrained Outcomes.” Frontiers in Human Neuroscience 8 (617): 1–14.
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    • Strenziok, Maren, Raja Parasuraman, Ellen Clarke, Dean S. Cisler, James C. Thompson, and Pamela M. Greenwood. 2014. “Neurocognitive Enhancement in Older Adults: Comparison of Three Cognitive Training Tasks to Test a Hypothesis of Training Transfer in Brain Connectivity.” NeuroImage 85, Part 3:1027–39.
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    • Smith-Ray, Renae L., Beth Makowski-Woidan, and Susan L. Hughes. 2014. “A Randomized Trial to Measure the Impact of a Community-Based Cognitive Training Intervention on Balance and Gait in Cognitively Intact Black Older Adults.” Health Education & Behavior 41 (1 suppl): 62S-69S.
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    • Sharpe, Chantelle, Amanda A. Holup, Kevin E. Hansen, and Jerri D. Edwards. 2014. “Does Self-Efficacy Affect Responsiveness to Cognitive Speed of Processing Training?” Journal of Aging and Health 26 (5): 786–806.
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    • Rebok, George W., Karlene Ball, Lin T. Guey, Richard N. Jones, Hae-Young Kim, Jonathan W. King, Michael Marsiske, et al. 2014. “Ten-Year Effects of the Advanced Cognitive Training for Independent and Vital Elderly Cognitive Training Trial on Cognition and Everyday Functioning in Older Adults.” Journal of the American Geriatrics Society 62 (1): 16–24.
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    • Mishra, Jyoti, Etienne de Villers-Sidani, Michael Merzenich, and Adam Gazzaley. 2014. “Adaptive Training Diminishes Distractibility in Aging across Species.” Neuron 84 (5): 1091–1103.
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    • González-Palau, Fátima, Manuel Franco, Panagiotis Bamidis, Raquel Losada, Esther Parra, Sokratis G. Papageorgiou, and Ana B. Vivas. 2014. “The Effects of a Computer-Based Cognitive and Physical Training Program in a Healthy and Mildly Cognitive Impaired Aging Sample.” Aging & Mental Health 18 (7): 838–46.
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    • Elliott, Amanda F., Melissa L. O’Connor, and Jerri D. Edwards. 2014. “Cognitive Speed of Processing Training in Older Adults with Visual Impairments.” Ophthalmic and Physiological Optics 34 (5): 509–18.
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    • Anderson, Samira, Travis White-Schwoch, Hee Jae Choi, and Nina Kraus. 2014. “Partial Maintenance of Auditory-Based Cognitive Training Benefits in Older Adults.” Neuropsychologia 62:286–96.
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    • Wolinsky, Fredric D., Mark W. Vander Weg, M. Bryant Howren, Michael P. Jones, and Megan M. Dotson. 2013. “A Randomized Controlled Trial of Cognitive Training Using a Visual Speed of Processing Intervention in Middle Aged and Older Adults.” PLoS ONE 8 (5): e61624.
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    • O’Brien, Jennifer L., Jerri D. Edwards, Nathan D. Maxfield, Carol L. Peronto, Victoria A. Williams, and Jennifer J. Lister. 2013. “Cognitive Training and Selective Attention in the Aging Brain: An Electrophysiological Study.” Clinical Neurophysiology 124 (11): 2198–2208.
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    • Jones, Richard N., Michael Marsiske, Karlene Ball, George Rebok, Sherry L. Willis, John N. Morris, and Sharon L. Tennstedt. 2013. “The ACTIVE Cognitive Training Interventions and Trajectories of Performance among Older Adults.” Journal of Aging and Health 25 (8 suppl): 186S-208S.
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    • Edwards, Jerri D., Christine L. Ruva, Jennifer L. O’Brien, Christine B. Haley, and Jennifer J. Lister. 2013. “An Examination of Mediators of the Transfer of Cognitive Speed of Processing Training to Everyday Functional Performance.” Psychology and Aging 28 (2): 314–21.
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    • Burge, Wesley K., Lesley A. Ross, Frank R. Amthor, William G. Mitchell, Alexander Zotov, and Kristina M. Visscher. 2013. “Processing Speed Training Increases the Efficiency of Attentional Resource Allocation in Young Adults.” Frontiers in Human Neuroscience 7 (684): 1–7.
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    • Belchior, Patrícia, Michael Marsiske, Shannon M. Sisco, Anna Yam, Daphne Bavelier, Karlene Ball, and William C. Mann. 2013. “Video Game Training to Improve Selective Visual Attention in Older Adults.” Computers in Human Behavior 29 (4): 1318–24.
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    • Ball, Karlene K., Lesley A. Ross, David L. Roth, and Jerri D. Edwards. 2013. “Speed of Processing Training in the ACTIVE Study: Who Benefits?” Journal of Aging and Health 25 (8 suppl): 65S-84S.
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    • Anderson, Samira, Travis White-Schwoch, Hee Jae Choi, and Nina Kraus. 2013. “Training Changes Processing of Speech Cues in Older Adults with Hearing Loss.” Frontiers in Systems Neuroscience 7 (97): 1–9.
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    • Anderson, Samira, Travis White-Schwoch, Alexandra Parbery-Clark, and Nina Kraus. 2013. “Reversal of Age-Related Neural Timing Delays with Training.” Proceedings of the National Academy of Sciences 110 (11): 4357–62.
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    • Szelag, Elzbieta, and Justyna Skolimowska. 2012. “Cognitive Function in Elderly Can Be Ameliorated by Training in Temporal Information Processing.” Restorative Neurology and Neuroscience 30 (5): 419–34.
      View article
    • Belchior, Patrícia, Michael Marsiske, Shannon Sisco, Anna Yam, and William Mann. 2012. “Older Adults’ Engagement with a Video Game Training Program.” Activities, Adaptation & Aging 36 (4): 269–79.
      View article
    • Zelinski, E. M., L. M. Spina, K. Yaffe, R. Ruff, R. F. Kennison, H. W. Mahncke, and G. E. Smith. 2011. “Improvement in Memory with Plasticity-Based Adaptive Cognitive Training (IMPACT): Results of the 3-Month Follow-Up.” Journal of the American Geriatrics Society 59:258–65.
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    • Wolinsky, Fredric D, Mark W Vander Weg, M Bryant Howren, Michael P Jones, Rene Martin, Tana M Luger, Kevin Duff, and Megan M Dotson. 2011. “Interim Analyses from a Randomised Controlled Trial to Improve Visual Processing Speed in Older Adults: The Iowa Healthy and Active Minds Study.” BMJ Open 1 (2): e000225.
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    • Wolinsky, Fredric D, Henry Mahncke, Mark W Vander Weg, Rene Martin, Frederick W Unverzagt, Karlene K Ball, Richard N Jones, and Sharon L Tennstedt. 2010. “Speed of Processing Training Protects Self-Rated Health in Older Adults: Enduring Effects Observed in the Multi-Site ACTIVE Randomized Controlled Trial.” International Psychogeriatrics / IPA 22 (3): 470–78.
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    • Berry, A S, T P Zanto, W C Clapp, J L Hardy, P B Delahunt, H W Mahncke, and A Gazzaley. 2010. “The Influence of Perceptual Training on Working Memory in Older Adults.” PLoS ONE 5 (7): e11537.
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    • Ball, K, J. D. Edwards, L. A. Ross, and G. McGwin Jr. 2010. “Cognitive Training Decreases Motor Vehicle Collision Involvement of Older Drivers.” Journal of the American Geriatrics Society 58 (11): 2107–13.
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    • Wolinsky, Fredric D, Mark W Vander Weg, René Martin, Frederick W Unverzagt, Sherry L Willis, Michael Marsiske, George W Rebok, John N Morris, Karlene K Ball, and Sharon L Tennstedt. 2009. “Does Cognitive Training Improve Internal Locus of Control among Older Adults?” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 65 (5): 591–98.
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    • Wolinsky, F. D., M. W. Vander Weg, R Martin, F. W. Unverzagt, K. K. Ball, R. N. Jones, and S. L. Tennstedt. 2009. “The Effect of Speed-of-Processing Training on Depressive Symptoms in ACTIVE.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 64 (4): 468–72.
      View article
    • Wolinsky, F D, H W Mahncke, M W Vander Weg, R Martin, F W Unverzagt, K K Ball, R N Jones, and S L Tennstedt. 2009. “The ACTIVE Cognitive Training Interventions and the Onset of and Recovery from Suspected Clinical Depression.” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 64 (5): 577–85.
      View article
    • Wolinsky, F. D., H. W. Mahncke, M. Kosinski, F. W. Unverzagt, D. M. Smith, R. N. Jones, A. Stoddard, and S. L. Tennstedt. 2009. “The ACTIVE Cognitive Training Trial and Predicted Medical Expenditures.” BMC Health Services Research 9 (109): 1–9.
      View article
    • Smith, G E, P Housen, K Yaffe, R Ruff, R F Kennison, H W Mahncke, and E M Zelinski. 2009. “A Cognitive Training Program Based on Principles of Brain Plasticity: Results from the Improvement in Memory with Plasticity-Based Adaptive Cognitive Training (IMPACT) Study.” Journal of the American Geriatrics Society 57 (4): 594–603.
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    • Edwards, J. D., P. B. Delahunt, and H. W. Mahncke. 2009. “Cognitive Speed of Processing Training Delays Driving Cessation.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 64 (12): 1262–67.
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    • Vance, D., J. Dawson, V. Wadley, J. Edwards, D. Roenker, M. Rizzo, and K. Ball. 2007. “The ACCELERATE Study: The Longitudinal Effect of Speed of Processing Training on Cognitive Performance of Older Adults.” Rehabilitation Psychology 52 (1): 89–96.
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    • Scalf, Paige E., Stanley J. Colcombe, Jason S. McCarley, Kirk I. Erickson, Maritza Alvarado, Jenny S. Kim, Ruchika P. Wadhwa, and Arthur F. Kramer. 2007. “The Neural Correlates of an Expanded Functional Field of View.” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 62 Spec No 1:32–44.
      View article
    • Wolinsky, Fredric D., Frederick W. Unverzagt, David M. Smith, Richard Jones, Anne Stoddard, and Sharon L. Tennstedt. 2006. “The ACTIVE Cognitive Training Trial and Health-Related Quality of Life: Protection That Lasts for 5 Years.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 61 (12): 1324–29.
      View article
    • Wolinsky, Fredric D., Frederick W. Unverzagt, David M. Smith, Richard Jones, Elizabeth Wright, and Sharon L. Tennstedt. 2006. “The Effects of the ACTIVE Cognitive Training Trial on Clinically Relevant Declines in Health-Related Quality of Life.” The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 61 (5): S281-287.
      View article
    • Willis, Sherry L., Sharon L. Tennstedt, Michael Marsiske, Karlene Ball, Jeffrey Elias, Kathy Mann Koepke, John N. Morris, et al. 2006. “Long-Term Effects of Cognitive Training on Everyday Functional Outcomes in Older Adults.” JAMA: The Journal of the American Medical Association 296 (23): 2805–14.
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    • Mahncke, H W, B B Connor, J Appelman, O N Ahsanuddin, J L Hardy, R A Wood, N M Joyce, T Boniske, S M Atkins, and M M Merzenich. 2006. “Memory Enhancement in Healthy Older Adults Using a Brain Plasticity-Based Training Program: A Randomized, Controlled Study.” Proceedings of the National Academy of Sciences 103 (33): 12523–28.
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    • Mahncke, H. W., A. Bronstone, and M. M. Merzenich. 2006. “Brain Plasticity and Functional Losses in the Aged: Scientific Bases for a Novel Intervention.” Progress in Brain Research 157:81–109.
      View article
    • Edwards, J. D, V. G. Wadley, D. E. Vance, K. Wood, D. L. Roenker, and K. K. Ball. 2005. “The Impact of Speed of Processing Training on Cognitive and Everyday Performance.” Aging & Mental Health 9 (3): 262–71.
      View article
    • Roenker, Daniel L., Gayla M. Cissell, Karlene K. Ball, Virginia G. Wadley, and Jerri D. Edwards. 2003. “Speed-of-Processing and Driving Simulator Training Result in Improved Driving Performance.” Human Factors 45 (2): 218–33.
      View article
    • Edwards, J. D., V. G. Wadley, R. S. Myers, D. L. Roenker, G. M. Cissell, and K. K. Ball. 2002. “Transfer of a Speed of Processing Intervention to near and Far Cognitive Functions.” Gerontology 48:329–40.
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    • Ball, Karlene, Daniel B. Berch, Karin F. Helmers, Jared B. Jobe, Mary D. Leveck, Michael Marsiske, John N. Morris, et al. 2002. “Effects of Cognitive Training Interventions with Older Adults: A Randomized Controlled Trial.” JAMA: The Journal of the American Medical Association 288 (18): 2271–81.
      View article

 

HEART FAILURE

                  • Gary, Rebecca A., Sudeshna Paul, Elizabeth Corwin, Brittany Butts, Andrew H. Miller, Kenneth Hepburn, and Drenna Waldrop. 2020. “Exercise and Cognitive Training Intervention Improves Self-Care, Quality of Life and Functional Capacity in Persons with Heart Failure.” Journal of Applied Gerontology, October, 0733464820964338.
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                  • Gary, R, S Paul, E Corwin, B Butts, A Miller, K Hepburn, and D Waldrop-Valverde. 2019. “Exercise and Cognitive Training as a Strategy to Improve Neurocognitive Outcomes in Heart Failure: A Pilot Study.”
                    View article
                  • Pressler, Susan J., Marita Titler, Todd M. Koelling, Penny L. Riley, Miyeon Jung, Lisa Hoyland-Domenico, David L. Ronis, et al. 2015. “Nurse-Enhanced Computerized Cognitive Training Increases Serum Brain-Derived Neurotropic Factor Levels and Improves Working Memory in Heart Failure.” Journal of Cardiac Failure 21 (8): 630–41.
                    View article
                  • Athilingam, Ponrathi, Jerri D. Edwards, Elise G. Valdes, Ming Ji, and Maya Guglin. 2015. “Computerized Auditory Cognitive Training to Improve Cognition and Functional Outcomes in Patients with Heart Failure: Results of a Pilot Study.” Heart & Lung: The Journal of Acute and Critical Care 44 (2): 120–28.
                    View article
                  • Ellis, Michelle L., Jerri D. Edwards, Lindsay Peterson, Rosalyn Roker, and Ponrathi Athilingam. 2014. “Effects of Cognitive Speed of Processing Training among Older Adults with Heart Failure.” Journal of Aging and Health 26 (4): 600–615.
                    View article
                  • Pressler, Susan J., Alison Martineau, Judith Grossi, Bruno Giordani, Todd M. Koelling, David L. Ronis, Penny L. Riley, Cheng-Chen Chou, Barbara J. Sullivan, and Dean G. Smith. 2013. “Healthcare Resource Use among Heart Failure Patients in a Randomized Pilot Study of a Cognitive Training Intervention.” Heart & Lung 42 (5): 332–338.
                    View article
                  • Pressler, Susan J., Barbara Therrien, Penny L. Riley, Cheng-Chen Chou, David L. Ronis, Todd M. Koelling, Dean G. Smith, Barbara Jean Sullivan, Ann-Marie Frankini, and Bruno Giordani. 2011. “Nurse-Enhanced Memory Intervention in Heart Failure: The MEMOIR Study.” Journal of Cardiac Failure 17 (10): 832–843.
                    View article

 

HIV-RELATED COGNITIVE DECLINE

                  • Vance, David E., Pariya L. Fazeli, Andres Azuero, Jennifer S. Frank, Virginia G. Wadley, James L. Raper, Caitlin N. Pope, and Karlene K. Ball. 2024. “A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study.” AIDS and Behavior 28 (10): 3300–3314.
                    View article
                  • Eaton, Andrew D., Jenny Hui, Marvelous Muchenje, Taylor Kon, Kate Murzin, Soo Chan Carusone, Nuelle Novik, Adria Quigley, Kristina Kokorelias, and Francisco Ibáñez-Carrasco. 2024. “Adapting Cognitive Remediation Group Therapy Online: Focus Groups with People Aging with HIV.” Journal of the International Association of Providers of AIDS Care 23.
                    View article
                  • Vance, David E., Pariya L. Fazeli, Andres Azuero, Sarah Khalidi, Jennifer S. Frank, Virginia G. Wadley, James L. Raper, Caitlin N. Pope, Alexandra E. Jacob, and Karlene K. Ball. 2023. “Two-Year Clinical Trial Examining the Effects of Speed of Processing Training on Everyday Functioning in Adults with Human Immunodeficiency Virus-Associated Neurocognitive Disorder (HAND) and Borderline HAND in the U.S. Deep South: Findings of the Think Fast Study.” Applied Neuropsychology: Adult, 1–14.
                    View article
                  • Eaton, Andrew D., Shelley L. Craig, Sean B. Rourke, Teresa Sota, John W. McCullagh, Barbara A. Fallon, and Sharon L. Walmsley. 2022. “Cognitive Remediation Group Therapy Compared to Mutual Aid Group Therapy for People Aging with HIV-Associated Neurocognitive Disorder: Randomized, Controlled Trial.” Social Work with Groups 45 (2): 116–31.
                    View article
                  • Vance, David E., Caitlin N. Pope, Pariya L. Fazeli, Andres Azuero, Jennifer S. Frank, Virginia G. Wadley, James L. Raper, Jun Y. Byun, and Karlene K. Ball. 2022. “A Randomized Clinical Trial on the Impact of Individually Targeted Computerized Cognitive Training on Quality of Life Indicators in Adults with Hiv-Associated Neurocognitive Disorder in the Southeastern United States.” Journal of the Association of Nurses in AIDS Care, January.
                    View article
                  • Vance, David E., Pariya L. Fazeli, Andres Azuero, Virginia G. Wadley, James L. Raper, and Karlene K. Ball. 2021. “Can Individualized-Targeted Computerized Cognitive Training Benefit Adults with HIV-Associated Neurocognitive Disorder? The Training On Purpose Study (TOPS).” AIDS and Behavior, March.
                    View article
                  • Vance, David E., Michael Jensen, Frida Tende, James L. Raper, Shannon Morrison, and Pariya L. Fazeli. 2018. “Individualized-Targeted Computerized Cognitive Training to Treat HIV-Associated Neurocognitive Disorder: An Interim Descriptive Analysis.” The Journal of the Association of Nurses in AIDS Care: JANAC 29 (4): 604–11.
                    View article
                  • Pope, C. N., D. Stavrinos, D. E. Vance, A. J. Woods, T. R. Bell, K. K. Ball, and P. L. Fazeli. 2018. “A Pilot Investigation on the Effects of Combination Transcranial Direct Current Stimulation and Speed of Processing Cognitive Remediation Therapy on Simulated Driving Behavior in Older Adults with HIV.” Transportation Research Part F: Traffic Psychology and Behaviour 58 (October): 1061–73.
                    View article
                  • Frain, Judy A., and Ling Chen. 2018. “Examining the Effectiveness of a Cognitive Intervention to Improve Cognitive Function in a Population of Older Adults Living with HIV: A Pilot Study.” Therapeutic Advances in Infectious Disease 5 (1): 19–28.
                    View article
                  • Kaur, Jaspreet, Joan E. Dodson, Laura Steadman, and David E. Vance. 2014. “Predictors of Improvement Following Speed of Processing Training in Middle-Aged and Older Adults with HIV: A Pilot Study.” The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses 46 (1): 23–33.
                    View article
                  • Vance, David E., Pariya L. Fazeli, Lesley A. Ross, Virginia G. Wadley, and Karlene K. Ball. 2012. “Speed of Processing Training with Middle-Age and Older Adults with HIV: A Pilot Study.” Journal of the Association of Nurses in AIDS Care 23 (6): 500–510.
                    View article

 

LONG COVID (MCI)

                  • Uswatte, Gitendra, Edward Taub, Karlene Ball, et al. 2025. “Long COVID Brain Fog Treatment: An Early-Phase Randomized Controlled Trial of Constraint-Induced Cognitive Therapy Signals Go.” Rehabilitation Psychology, ahead of print.
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MILD COGNITIVE IMPAIRMENT (MCI)

                      • Carvalho, Cíntia Monteiro, Bruno Costa Poltronieri, Karin Reuwsaat, Maria Eduarda Alves Reis, and Rogerio Panizzutti. 2025. “Digital Cognitive Training for Functionality in Mild Cognitive Impairment: A Randomized Controlled Clinical Trial.” GeroScience, January.
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                      • Macchiarelli, Justin E, Courtney Dowell-Esquivel, Alejandro Martinez, Andrea Rivera-Molina, Annalee Mueller, Peter Kallestrup, Sara J. Czaja, and Philip D. Harvey. 2024. “Association of Racial Status and Training Language with Baseline Performance and Training Gains During Computerized Training of Technology-Related Everyday Functional Skills In Older Adults.” The American Journal of Geriatric Psychiatry: Open Science, Education, and Practice.
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                      • Harvey, Philip D., Courtney Dowell-Esquivel, Justin E. Macchiarelli, Alejandro Martinez, Peter Kallestrup, and Sara J. Czaja. 2024. “Early Prediction of Mastery of a Computerized Functional Skills Training Program in Participants with Mild Cognitive Impairment.” International Psychogeriatrics, 1–12.
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                      • McMaster, M., S. Kim, L. Clare, S. J. Torres, N. Cherbuin, and K. J. Anstey. 2023. “The Feasibility of a Multidomain Dementia Risk Reduction Randomised Controlled Trial for People Experiencing Cognitive Decline: The Body, Brain, Life for Cognitive Decline (BBL-CD).” Aging & Mental Health, 1–9.
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                      • Chwa, Won Jong, Cyrus A. Raji, Kat Toups, Ann Hathaway, Deborah Gordon, Henrianna Chung, Alan Boyd, et al. 2023. “Longitudinal White and Gray Matter Response to Precision Medicine-Guided Intervention for Alzheimer’s Disease.” Journal of Alzheimer’s Disease: JAD 96 (3): 1051–58.
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                      • Chuang, I-Ching, Hui-Yan Chiau, Wan-Wen Liao, Yih-Ru Wu, Chih-Hung Chang, and Ching-Yi Wu. 2023. “Effects of Computer-Based Cognitive Training Combined with Physical Training for Older Adults with Cognitive Impairment: A Four-Arm Randomized Controlled Trial.” Digital Health 9.
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                      • Toups, Kat, Ann Hathaway, Deborah Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, et al. 2022. “Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.” Journal of Alzheimer’s Disease 88:1411–21.
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                      • Harvey, Philip D., Matthew Zayas-Bazan, Lize Tibiriçá, Peter Kallestrup, and Sara J. Czaja. 2022. “Improvements in Cognitive Performance With Computerized Training in Older People With and Without Cognitive Impairment: Synergistic Effects of Skills-Focused and Cognitive-Focused Strategies.” The American Journal of Geriatric Psychiatry 30 (6): 717–26.
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                      • Cuc, Andrea V., Dona EC Locke, Noah Duncan, Julie A. Fields, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, Glenn E. Smith, and Melanie Chandler. 2017. “A Pilot Randomized Trial of Two Cognitive Rehabilitation Interventions for Mild Cognitive Impairment: Caregiver Outcomes.” International Journal of Geriatric Psychiatry 32 (12): e180–87.
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                      • Chen, Quanjing, Adam Turnbull, Martin Cole, Zhengwu Zhang, and Feng V. Lin. 2022. “Enhancing Cortical Network-Level Participation Coefficient as a Potential Mechanism for Transfer in Cognitive Training in AMCI.” NeuroImage, March, 119124.
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                      • Levy, Shellie-Anne, Glenn Smith, Liselotte De Wit, Brittany DeFeis, Gelan Ying, Priscilla Amofa, Dona Locke, et al. 2022. “Behavioral Interventions in Mild Cognitive Impairment (MCI): Lessons from a Multicomponent Program.” Neurotherapeutics 19 (1): 117–31.
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                      • Shandera-Ochsner, Anne L., Melanie J. Chandler, Dona E. Locke, Colleen T. Ball, Julia E. Crook, Vaishali S. Phatak, and Glenn E. Smith. 2021. “Comparative Effects of Physical Exercise and Other Behavioral Interventions on Functional Status Outcomes in Mild Cognitive Impairment.” Journal of the International Neuropsychological Society : JINS 27 (8): 805–12.
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                      • Phatak, Vaishali S., Glenn E. Smith, Dona Locke, Anne Shandera-Ochsner, Pamela M. Dean, Colleen Ball, Gianna Gutierrez, and Melanie J. Chandler. 2021. “Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment.” Brain Sciences 11 (8): 988.
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                      • Lin, Feng, Ye Tao, Quanjing Chen, Mia Anthony, Zhengwu Zhang, Duje Tadin, and Kathi L. Heffner. 2020. “Processing Speed and Attention Training Modifies Autonomic Flexibility: A Mechanistic Intervention Study.” NeuroImage, 116730.
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                      • Chen, Quanjing, Haichuan Yang, Brian Rooks, Mia Anthony, Zhengwu Zhang, Duje Tadin, Kathi L. Heffner, and Feng V. Lin. 2020. “Autonomic Flexibility Reflects Learning and Associated Neuroplasticity in Old Age.” Human Brain Mapping 41 (13): 3608–19.
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                      • Czaja, Sara J., Peter Kallestrup, and Philip D. Harvey. 2020. “Evaluation of a Novel Technology-Based Program Designed to Assess and Train Everyday Skills in Older Adults.” Innovation in Aging 4 (6).
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                      • McMaster, Mitchell, Sarang Kim, Linda Clare, Susan J. Torres, Nicolas Cherbuin, Catherine DʼEste, and Kaarin J. Anstey. 2020. “Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD).” Journal of the American Geriatrics Society, September.
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                      • Valdés, Elise G., Ross Andel, Jennifer J. Lister, Alyssa Gamaldo, and Jerri D. Edwards. 2017. “Can Cognitive Speed of Processing Training Improve Everyday Functioning among Older Adults with Psychometrically Defined Mild Cognitive Impairment?” Journal of Aging and Health 31 (4): 595–610.
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                      • Lin, Feng, Kathi L Heffner, Ping Ren, and Duje Tadin. 2017. “A Role of the Parasympathetic Nervous System in Cognitive Training.” Current Alzheimer Research 14 (7): 784–789.
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                      • Lin, Feng, Kathi L. Heffner, Ping Ren, Madalina E. Tivarus, Judith Brasch, Ding-Geng Chen, Mark Mapstone, Anton P. Porsteinsson, and Duje Tadin. 2016. “Cognitive and Neural Effects of Vision-Based Speed-of-Processing Training in Older Adults with Amnestic Mild Cognitive Impairment: A Pilot Study.” Journal of the American Geriatrics Society 64 (6): 1293–98.
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                      • Klados, Manousos A., Charis Styliadis, Christos A. Frantzidis, Evangelos Paraskevopoulos, and Panagiotis D. Bamidis. 2016. “Beta-Band Functional Connectivity Is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training.” Frontiers in Neuroscience 10 (55): 1–12.
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                      • Gooding, Amanda L., Jimmy Choi, Joanna M. Fiszdon, Kirsten Wilkins, Paul D. Kirwin, Christopher H. van Dyck, Davangere Devanand, Morris D. Bell, and Monica Rivera Mindt. 2015. “Comparing Three Methods of Computerised Cognitive Training for Older Adults with Subclinical Cognitive Decline.” Neuropsychological Rehabilitation 26 (5–6): 810–21.
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                      • Bamidis, Panagiotis D., Patrick Fissler, Sokratis G. Papageorgiou, Vasiliki Zilidou, Evdokimos I. Konstantinidis, Antonis S. Billis, Evangelia Romanopoulou, et al. 2015. “Gains in Cognition through Combined Cognitive and Physical Training: The Role of Training Dosage and Severity of Neurocognitive Disorder.” Frontiers in Aging Neuroscience 7 (152): 1–15.
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                      • Styliadis, Charis, Panagiotis Kartsidis, Evangelos Paraskevopoulos, Andreas A. Ioannides, and Panagiotis D. Bamidis. 2015. “Neuroplastic Effects of Combined Computerized Physical and Cognitive Training in Elderly Individuals at Risk for Dementia: An Eloreta Controlled Study on Resting States.” Neural Plasticity 2015 (April): e172192.
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                      • Locke, Dona EC, Melanie Chandler Greenaway, Noah Duncan, Julie A. Fields, Andrea V. Cuc, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, and Glenn E. Smith. 2014. “A Patient-Centered Analysis of Enrollment and Retention in a Randomized Behavioral Trial of Two Cognitive Rehabilitation Interventions for Mild Cognitive Impairment.” The Journal of Prevention of Alzheimer’s Disease 1 (3): 143.
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                      • Valdes, Elise G., Melissa L. O’Connor, and Jerri D. Edwards. 2012. “The Effects of Cognitive Speed of Processing Training among Older Adults with Psychometrically-Defined Mild Cognitive Impairment.” Current Alzheimer Research 9 (9): 999–1009. https://doi.org/10.2174/156720512803568984
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                      • Rosen, A.C., L. Sugiura, J.H. Kramer, S. Whitfield-Gabrieli, and J.D. Gabrieli. 2011. “Cognitive Training Changes Hippocampal Function in Mild Cognitive Impairment: A Pilot Study.” Journal of Alzheimer’s Disease 26: 349–357.
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                      • Barnes, Deborah E, Kristine Yaffe, Nataliya Belfor, William J Jagust, Charles DeCarli, Bruce R Reed, and Joel H Kramer. 2009. “Computer-Based Cognitive Training for Mild Cognitive Impairment: Results from a Pilot Randomized, Controlled Trial.” Alzheimer Disease and Associated Disorders 23 (3): 205–10.
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                      • Unverzagt, Frederick W., Linda Kasten, Kathy E. Johnson, George W. Rebok, Michael Marsiske, Kathy Mann Koepke, Jeffrey W. Elias, et al. 2007. “Effect of Memory Impairment on Training Outcomes in ACTIVE.” Journal of the International Neuropsychological Society : JINS 13 (6): 953–60.
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MULTIPLE SCLEROSIS

                  • Muccio, Marco, Giuseppina Pilloni, Lillian Walton Masters, Peidong He, Lauren Krupp, Abhishek Datta, Marom Bikson, Leigh Charvet, and Yulin Ge. 2024. “Simultaneous and Cumulative Effects of TDCS on Cerebral Metabolic Rate of Oxygen in Multiple Sclerosis.” Frontiers in Human Neuroscience 18.
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                  • Ziccardi, Stefano, Tom Fuchs, Michael G Dwyer, Robert Zivadinov, Hanneke E Hulst, Massimiliano Calabrese, and Ralph HB Benedict. 2023. “Cognitive Phenotypes Predict Response to Restorative Cognitive Rehabilitation in Multiple Sclerosis.” Multiple Sclerosis Journal.
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                  • Chiaravalloti, Nancy D., Silvana L. Costa, Nancy B. Moore, Kristen Costanza, and John DeLuca. 2022. “The Efficacy of Speed of Processing Training for Improving Processing Speed in Individuals with Multiple Sclerosis: A Randomized Clinical Trial.” Journal of Neurology 269 (7): 3614–24.
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                  • Fuchs, Tom A., Stefano Ziccardi, Ralph H. B. Benedict, Alexander Bartnik, Amy Kuceyeski, Leigh E. Charvet, Devon Oship, et al. 2020. “Functional Connectivity and Structural Disruption in the Default-Mode Network Predicts Cognitive Rehabilitation Outcomes in Multiple Sclerosis.” Journal of Neuroimaging 30 (4): 523–30.
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                  • Vilou, Irini, and Christos Bakirtzis. 2020. “Computerized cognitive rehabilitation for treatment of cognitive impairment in multiple sclerosis: an explorative study.” Journal of Integrative Neuroscience 19 (2): 341–47.
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                  • Shaw, Michael, Giuseppina Pilloni, and Leigh Charvet. 2020. “Delivering Transcranial Direct Current Stimulation Away from Clinic: Remotely Supervised TDCS.” Military Medicine 185 (Supplement_1): 319–25.
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                  • Barker, Lindsay, Brian C. Healy, Emily Chan, Kaitlynne Leclaire, and Bonnie I. Glanz. 2019. “A Pilot Study to Assess At-Home Speed of Processing Training for Individuals with Multiple Sclerosis.” Multiple Sclerosis International 2019.
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                  • Fuchs, Tom A., Stefano Ziccardi, Michael G. Dwyer, Leigh E. Charvet, Alexander Bartnik, Rebecca Campbell, Jose Escobar, et al. 2019. “Response Heterogeneity to Home-Based Restorative Cognitive Rehabilitation in Multiple Sclerosis: An Exploratory Study.” Multiple Sclerosis and Related Disorders 34 (September): 103–11.
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                  • Charvet, Leigh E., Jie Yang, Michael T. Shaw, Kathleen Sherman, Lamia Haider, Jianjin Xu, and Lauren B. Krupp. 2017. “Cognitive Function in Multiple Sclerosis Improves with Telerehabilitation: Results from a Randomized Controlled Trial.” PLOS ONE 12 (5): e0177177.
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PARKINSON’S DISEASE

                      • Hoffman, Lisa, Nicholas D. Burt, Nicholas R. Piniella, Madison Baker, Nicole Volino, Saeed Yasin, Min-Kyung Jung, Adena Leder, and Amber Sousa. 2023. “Efficacy and Feasibility of Remote Cognitive Remediation Therapy in Parkinson’s Disease: A Randomized Controlled Trial.” Edited by Giovanni Mirabella. Parkinson’s Disease, 1–10.
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                      • Manenti, Rosa, Maria Sofia Cotelli, Chiara Cobelli, Elena Gobbi, Michela Brambilla, Danila Rusich, Antonella Alberici, Alessandro Padovani, Barbara Borroni, and Maria Cotelli. 2018. “Transcranial Direct Current Stimulation Combined with Cognitive Training for the Treatment of Parkinson Disease: A Randomized, Placebo-Controlled Study.” Brain Stimulation 11 (6): 1251–62.
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                      • Valdés, Elise G., Melissa L. O’Connor, Ergun Y. Uc, Robert A. Hauser, Ross Andel, and Jerri D. Edwards. 2016. “Use, Maintenance, and Dose Effects of Cognitive Speed of Processing Training in Parkinson’s Disease.” International Journal of Neuroscience TBA (TBA): 1–8.
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                      • Edwards, Jerri D., Robert A. Hauser, Melissa L. O’Connor, Elise G. Valdés, Theresa A. Zesiewicz, and Ergun Y. Uc. 2013. “Randomized Trial of Cognitive Speed of Processing Training in Parkinson Disease.” Neurology 81 (15): 1284–90.
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SCHIZOPHRENIA & RELATED PSYCHOSES

                      • Adcock RA, Dale C et al. When top-down meets bottom-up: Auditory training enhances verbal memory in schizophrenia. Schizophrenia Bulletin. 2009 Nov;35(6):1132-41. 
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                      • Ahmed AO, Hunter KM, Goodrum NM, et al. A randomized study of cognitive remediation for forensic and mental health patients with schizophrenia.Journal of Psychiatric Research. 2015. 
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                      • Bell, MD, Choi KH, Cyer C, Wexler BE. Benefits of cognitive remediation and supported employment for schizophrenia patients with poor community functioning. Psychiatric Services. 2014 Apr;65(4):469-475. 
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                      • Bell, MD, Zito W, Grieg T, Wexler BE. Neurocognitive enhancement therapy with vocational services: Work outcomes at two-year follow-up. Schizophrenia Research. 2008 Oct;105(1-3):18-29. 
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                      • Dodell-Feder D, Tully LM, Hooker CI. Social impairment in schizophrenia: New approaches for treating a persistent problem. Current Opinion in Psychiatry. 2015 May;28(3):236-42. 
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                      • Fisher M, Loewy R et al. Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia. Annual Review of Clinical Psychology. 2013;9:435-63. 
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                      • Fisher M, Loewy R et al. Neuroplasticity-based auditory training via laptop computer improves cognition in young individuals with recent onset schizophrenia. Schizophrenia Bulletin. 2015 Jan;41(1):250-8. 
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                      • Fisher M, Holland C, Merzenich MM, Vinogradov S. Using neuroplasticity-based auditory training to improve verbal memory in schizophrenia. American Journal of Psychiatry. 2009 Jul;166(7):805-11. 
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                      • Fisher M, Holland C, Subramaniam K, Vinogradov S. Neuroplasticity-based cognitive training in schizophrenia: An interim report on the effects 6 months later. Schizophrenia Bulletin. 2010 Jul;36(4):869-79. 
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                      • Fisher M, Mellon SH, Wolkowitz O, Vinogradov S. Neuroscience-informed auditory training in schizophrenia: A final report of the effects on cognition and serum brain-derived neurotrophic factor. Schizophrenia Research: Cognition. 2016;3:1-7
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                      • Green, MF. New possibilities in cognition enhancement for schizophrenia. 2009 Jul;166(7):749-52. 
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                      • Grieg TC, Zito W et al. Improved cognitive function in schizophrenia after one year of cognitive training and vocational services. Schizophrenia Research. 2007 Nov;96(1-3):156-61. 
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                      • Hooker CI, Bruce L et al. Neural activity during emotion recognition after combined cognitive plus social cognitive training in schizophrenia. Schizophrenia Research. 2012 Aug;139(1-3):53-9. 
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                      • Hooker CI, Bruce L et al. The influence of combined cognitive plus social-cognitive training on amygdala response during face emotion recognition in schizophrenia. Psychiatry Research. 2013 Aug 30;213(2):99-107. 
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                      • Keefe RSE, Vinogradov S et al. Feasibility and pilot efficacy results from the multisite Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) randomized control trial. Journal of Clinical Psychiatry. 2012 Jul;73(7):1016-1022. 
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                      • Merzenich MM, Van Vleet TM, Nahum M. Brain plasticity-based therapeutics. Frontiers in Human Neuroscience. 2014 Jun 27;8:385. 
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                      • Nahum M, Fisher M et al. A novel, online social cognitive training program for young adults with schizophrenia: A pilot study. Schizophrenia Research Cognition. 2014 Mar 1;1(1):e11-e19. 
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                      • Panizzutti R, Hamilton SP, Vinogradov S. Genetic correlate of cognitive training response in schizophrenia. Neuropharmacology. 2013;64:264-7. 
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                      • Popov T, Jordanov T et al. Specific cognitive training normalized auditory sensory gating in schizophrenia: A randomized trial. Biological Psychiatry. 2011 Mar 1;69(5):465-71. 
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                      • Popov T, Rockstroh B et al. Adjusting brain dynamics in schizophrenia by means of perceptual and cognitive training. PLoS One. 2012;7(7):e39051. 
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                      • Popov TG, Carolus A, Schubring D, Popova P, Miller GA, Rockstroh BS. Targeted training modifies oscillatory brain activity in schizophrenia patients. NeuroImage: Clinical. 2015;7:807-814. 
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                      • Sacks S, Fisher M et al. Combining computerized social cognitive training with neuroplasticity-based auditory training in schizophrenia. Clinical Schizophrenia & Related Psychoses. 2013 Summer;7(2):78-86A. 
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                      • Subramaniam K, Luks TL et al. Computerized cognitive training restores neural activity within the reality monitoring network in schizophrenia. Neuron. 2012 Feb 23;73:842-853. 
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                      • Subramaniam K, Luks TL et al. Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains. NeuroImage. 2014 Oct 1;99:281-92. 
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                      • Surti TS, Corbera S, Bella MD, Wexler BE. Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia. Schizophrenia Research. 2011 Nov;132(2-3):131-4. 
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                      • Vinogradov S, Fisher M et al. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biological Psychiatry. 2009 Sep 15;66(6):549-53. 
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                      • Vinogradov S, Fisher M et al. The cognitive cost of anticholinergic burden: Decreased response to cognitive training in schizophrenia. American Journal of Psychiatry. 2009 Sep;166(9):1055-62. 
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STROKE

                      • Liu, Chia-Lun, Shou-Hsien Huang, Wei-Chun Wang, Chih-Kuang Chen, Ken-Hsien Su, and Ching-Yi Wu. 2024. “Characterizing Two Hybrid Exercise-Cognitive Training Interventions with Neurophysiological and Behavioral Indexes in Post-Stroke Patients with Cognitive Dysfunction: A Randomized Controlled Trial.” IEEE Transactions on Neural Systems and Rehabilitation Engineering 32:3913–22.
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                      • Yeh, Ting-Ting, Ku-Chou Chang, Jiun-Jie Wang, Wei-Che Lin, and Ching-Yi Wu. 2023. “Neuroplastic Changes Associated With Hybrid Exercise-Cognitive Training in Stroke Survivors With Mild Cognitive Decline: A Randomized Controlled Trial.” Neurorehabilitation and Neural Repair 37 (9): 662–73.
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                      • Yeh, Ting-Ting, Ku-Chou Chang, Ching-Yi Wu, Chao-Jung Chen, and I.-Ching Chuang. 2022. “Clinical Efficacy of Aerobic Exercise Combined with Computer-Based Cognitive Training in Stroke: A Multicenter Randomized Controlled Trial.” Topics in Stroke Rehabilitation 29 (4): 255–64.
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                      • Wanqin, Mary, and Li Ma. 2022. “Effect of BrainHQ visual rehabilitation training on memory function of patients with cerebral infarction.” International Medical and Health Herald 28 (10): 1458–62.
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                      • Van Vleet, Thomas, Paolo Bonato, Eric Fabara, Sawsan Dabit, Sarah-Jane Kim, Christopher Chiu, Antonio Luigi Bisogno, Michael Merzenich, Maurizio Corbetta, and Joseph DeGutis. 2020. “Alertness Training Improves Spatial Bias and Functional Ability in Spatial Neglect.” Annals of Neurology, August.
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                      • Yeh, Ting-ting, Ku-chou Chang, and Ching-yi Wu. 2019. “The Active Ingredient of Cognitive Restoration: A Multicenter Randomized Controlled Trial of Sequential Combination of Aerobic Exercise and Computer-Based Cognitive Training in Stroke Survivors with Cognitive Decline.” Archives of Physical Medicine and Rehabilitation 100 (5): 821–27.
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                      • Wang, Jing, Ronghua Mao, Changxiang Chen, Shuxing Li, Min Zhang, and Na Dou. 2016. “BrainHQ visual training can improve the memory of stroke survivors.” Chinese Journal of Physical Medicine and Rehabilitation, 576–79.
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                      • Ronghua, Mao, Hao Jun Xi, and Chen Xiang Long. 2016. “Effects of BrainHQ Visual Training on Memory Function in Stroke Patients” 3: 312–15.
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                      • Mao, Ronghua, and Chen Xiang Long. 2016. “Effects of BrainHQ Visual Training on Balance Function in Stroke Patients” 5: 544–46.
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                      • Mao, Ronghua, Changxiang Chen, Dan Li, Shuxing Li, and Min Zhang. 2015. “Intervention Effect of BrainHQ Visual Training on Depressive Symptom in Patients with Post Stroke Depression.” Chinese Journal of Behavioral Medical Science 24 (12): 1097–99.
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                      • Chen, Chang-Xiang, Rong-Hua Mao, Shu-Xing Li, Ya-Ning Zhao, and Min Zhang. 2015. “Effect of Visual Training on Cognitive Function in Stroke Patients.” International Journal of Nursing Sciences 2 (4): 329–333.
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                      • Van Vleet, Thomas M., and Joseph M. DeGutis. 2013. “Cross-Training in Hemispatial Neglect: Auditory Sustained Attention Training Ameliorates Visual Attention Deficits.” Cortex 49 (3): 679–690.
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                      • DeGutis, Joseph M., and Thomas M. Van Vleet. 2010. “Tonic and Phasic Alertness Training: A Novel Behavioral Therapy to Improve Spatial and Non-Spatial Attention in Patients with Hemispatial Neglect.” Frontiers in Human Neuroscience 4 (60): 1–17.
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SUBSTANCE-USE DISORDERS

                      • Bell, Morris D., Bharath Muppala, Andrea J. Weinstein, David Ciosek, Brian Pittman, Ismene Petrakis, and Joanna M. Fiszdon. 2020. “Randomized Clinical Trial of Cognitive Remediation Therapy with Work Therapy in the Early Phase of Substance Use Disorder Recovery for Older Veterans: 12-Month Follow-Up.” Journal of Substance Abuse Treatment 112 (May): 17–22.
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                      • Bell, Morris D., Holly B. Laws, and Ismene B. Petrakis. 2016. “A Randomized Controlled Trial of Cognitive Remediation and Work Therapy in the Early Phase of Substance Use Disorder Recovery for Older Veterans: Neurocognitive and Substance Use Outcomes.” Psychiatric Rehabilitation Journal 40 (1): 94–102.
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                      • Bell, Morris D., Nicholas A. Vissicchio, and Andrea J. Weinstein. 2016. “Cognitive Training and Work Therapy for the Treatment of Verbal Learning and Memory Deficits in Veterans with Alcohol Use Disorders.” Journal of Dual Diagnosis 12 (1): 83–89.
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TINNITUS

                      • Kallogjeri, Dorina, Jay F. Piccirillo, Edward Spitznagel, Sandra Hale, Joyce E. Nicklaus, Frances Mei Hardin, Joshua S. Shimony, Rebecca S. Coalson, and Bradley L. Schlaggar. 2017. “Cognitive Training for Adults with Bothersome Tinnitus.” JAMA Otolaryngology-- Head & Neck Surgery 143 (5): 443–51.
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TRAUMATIC BRAIN INJURY (TBI)

                      • Agnoli, Sam, Henry Mahncke, Sarah-Jane Grant, Zachary T. Goodman, William P. Milberg, Michael Esterman, and Joseph DeGutis. 2024. “Negative Global Metacognitive Biases Are Associated with Depressive and Posttraumatic Stress Disorder Symptoms and Improve with Targeted or Game-Based Cognitive Training.” Neuropsychology 38 (7): 622–36.
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                      • Lindsey, Hannah M., Mariana Lazar, Giulia Mercuri, Joseph F. Rath, Tamara Bushnik, Steven Flanagan, and Gerald T. Voelbel. 2022. “The Effects of Plasticity-Based Cognitive Rehabilitation on Resting-State Functional Connectivity in Chronic Traumatic Brain Injury: A Pilot Study.” NeuroRehabilitation Preprint (Preprint): 1–18.
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                      • Voelbel, Gerald T., Hannah M. Lindsey, Giulia Mercuri, Tamara Bushnik, and Joseph Rath. 2021. “The Effects of Neuroplasticity-Based Auditory Information Processing Remediation in Adults with Chronic Traumatic Brain Injury.” NeuroRehabilitation, August.
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                      • Mahncke, Henry W, Joseph DeGutis, Harvey Levin, Mary R Newsome, Morris D Bell, Chad Grills, Louis M French, et al. 2021. “A Randomized Clinical Trial of Plasticity-Based Cognitive Training in Mild Traumatic Brain Injury.” Brain, no. awab202 (July).
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                      • Sharma, Bhanu, Jennifer C. Tomaszczyk, Deirdre Dawson, Gary R. Turner, Brenda Colella, and Robin E. A. Green. 2017. “Feasibility of Online Self-Administered Cognitive Training in Moderate–Severe Brain Injury.” Disability and Rehabilitation 39 (14): 1380–90.
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                      • O’Neil-Pirozzi, Therese, and Henry Hsu. 2016. “Feasibility and Benefits of Computerized Cognitive Exercise to Adults with Chronic Moderate-to-Severe Cognitive Impairments Following an Acquired Brain Injury: A Pilot Study” 30 (13–14): 1617–25.
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                      • Sullivan, Katherine W., Julia E. Quinn, Michael Pramuka, Laura A. Sharkey, and Louis M. French. 2012. “Outcomes from a Pilot Study Using Computer-Based Rehabilitative Tools in a Military Population.” Annual Review of Cybertherapy and Telemedicine 2012: Advanced Technologies in the Behavioral, Social and Neurosciences 181: 71–77.
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                      • Lebowitz, Matthew S., Kristen Dams-O’Connor, and Joshua B. Cantor. 2012. “Feasibility of Computerized Brain Plasticity-Based Cognitive Training after Traumatic Brain Injury.” Journal of Rehabilitation Research and Development 49 (10): 1547–1556.
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WORKPLACE

              • Hamilton, Joseph A., Gary Lambert, Joel Suss, and Adam T. Biggs. 2019. “Can Cognitive Training Improve Shoot/Don’t-Shoot Performance? Evidence from Live Fire Exercises.” The American Journal of Psychology 132 (2): 179–94.
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              • Miller, Steven L., Suhas Chelian, Will McBurnett, Winnie Tsou, and Amy A. Kruse. 2019. “An Investigation of Computer-Based Brain Training on the Cognitive and EEG Performance of Employees*.” 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), July, 518–21.
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              • Walters, Jim, Stanley E. Sheft, Mark A. Stellmack, and Anna Abele. 2019. “Improving Attentiveness: Effect of Cognitive Training on Sustained Attention Measures.” Professional Safety 64 (04): 31–35.
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